Wednesday, September 2, 2020

The Evolution of Science Fiction Essay -- Literature

Notwithstanding decades between their works, the likenesses between H.G. Wells and P.K. Dick are various and incorporate the way that the two creators were a long ways relatively revolutionary, had desires with respect to the universe and a future electronic period to come, had a subject spinning around a far off planet, and tested mankind. Both sci-fi creators were past their time. Wells had the capacity of â€Å"lifting up our fathers’ hearts with trusts, energizing them with the inclination that another world was at the purpose of being conceived and they were to acquire itâ€Å" (Dickson 17). All through the entirety of his works, P.K. Dick â€Å"focused on passing on reality of his many-faceted dreams without respect for basic desires and type conventions† (Mackey 128). It is said that â€Å"knowledge of Dick’s life story is basic to a comprehension of his work† (Umland 2). This also is like Wells. The two creators had intriguing existences and each discovered their own exceptional method to join their occasions and enthusiasm into their functions as exhibited by their different books and short stories. So as to completely see each creators perspectives, style, and in particular to set up ethos, one should initially comprehend the creators life. Dick and Wells were extraordinarily affected by their general surroundings. Regardless of whether it be clear or not, Dick incorporated his background into his books. He likewise included his very own considerable lot individual enthusiasm into the book. Wells compositions were for the most part affected by his own perspectives, assessments, and intrigue. It is anything but difficult to expect that a book was composed just off a smart thought in any case, there is regularly more to it. A hidden intrigue, an endeavored degree, a sudden experience. In 1949, Dick started examining reasoning at the University of California Berkley (1... ...rld, there is power in numbers and we can lead people in the future further, into the sci-fi world, yet science itself. In spite of almost 75% of a century between their compositions, the thoughts these two brilliant creators had were comparable from various perspectives. The two of them provoked science and society as far as possible. Works Cited Dick, Philip K. Do Androids Dream of Electric Sheep. New York: Random House, 1968. Print. Dickson, Lovat. H. G. Wells: His Turbulent Life and Times. New York: Lovat Dickson (?), 1969. Print. Mackey, Douglas A. Philip K. Dick. Massachusetts: Twayne, 1988. Print Wells, H. G. â€Å"A Story of the Days to Come.† 28 Science Fiction Stories. New York: Dover, 1952. 730-820. Priint. Wells, H. G. â€Å"The Time Machine.† The Complete Short Stories of H. G. Wells. London: Ernest Benn Limited, 1966. 9-91. Print.

Saturday, August 22, 2020

buy custom Post-Traumatic Stress Disorders essay

purchase custom Post-Traumatic Stress Disorders article Post-horrible Stress Disorders (PTSD) can be portrayed as mental issue that are experienced after an introduction to an upsetting occasion, for example, war, plane squash, abusive behavior at home, tremors and so forth. At the point when one is presented to such sickening occasions, s/he takes a serious decent measure of time to overlook and during that period, the casualty encounters organic and mental changes. From the beginning of time, wars have been known to trigger mental issues particularly to officers who subsequent to getting back; they become incapable to conform to home life after the war. This work is intended to investigate on the Post-Traumatic Stress Disorders that are experienced by the Iraq War veterans, with extraordinary spotlight on the causes, the Iraq conditions that added to these clutters, the manifestations of PTSD just as the how the war influenced the officers and their families. The work will likewise give the insights on the troopers who got back with men tal issues after the war. The vast majority of the veteran troopers were sent to proceed to help in battling the Iraq War. Anyway the vast majority of them got back with indications of PTSD. This was because of a few factors that added to the huge number of veteran fighters experiencing PTSD. A portion of these remember readiness for which a portion of the fighters feel regretful and irate that they didn't get enough arrangements on the most proficient method to deal with certain circumstances, for example, presentation to natural and atomic weapons. In such circumstances, they got vulnerable and this consistently spooky them that they were inadequate during the war. Thusly it was this persevering displeasure and the sentiment of blameworthy that expanded the casualties dangers for PTSD (Litz and Orsilo 25). Another reason for the numerous mental issues experienced by the veteran war members is introduction. The Iraq war included an increasingly ordinary presentation to weapon discharging subsequently one was restless that he might be shot by the adversary, be discharged inadvertently by an associate or shoot somebody. A large portion of them were additionally presented to seeing a companion kicking the bucket, wounds and so forth. Every one of these recollections stick in their psyches and after the war; it gets hard for them to recall in this manner they continue frequenting them (Litz and Orsilo 25). The consequence of the war may likewise be a genuine motivation of the mental issues experienced by the veterans. The repercussions presentation to seeing and taking care of collections of dead warriors and regular citizens, hints of biting the dust ladies and men sobbing for their lives, smell of disintegrating bodies and so forth were exceptionally discouraging and upsetting (Litz and Orsilo 25). The introduction to organic, compound and radiological weapons likewise influenced the strength of these troopers incessantly. A portion of the fighters that were presented to these substance endured ceaseless mental and mental issue therefore (Litz and Orsilo 26). Be that as it may, while the majority of the mental issues were because of the previously mentioned factors, the conditions in Iraq additionally added somewhat. The working and everyday environments were not favorable in the combat area. Troopers needed to adapt and live to weights and disturbances associated with life. They encountered weariness because of the long working days; resting less and working for a long time. They needed to get up ahead of schedule and rest extremely late, worn out yet expected to get ready for the next days work (Litz and Orsilo 26). They additionally experienced negative atmosphere; being in a remote land, they needed to change in accordance with new climatic conditions. The officers additionally needed to work with the accessible hardware which was now and then not adequate for every one of them as the stores run out. They likewise needed to eat remote and now and again unwanted food since they were in outside land, in this way they had to adjust to va rious culture and nourishments (Litz and Orsilo 26). Despite the fact that clearly these conditions are non-damaging, they strain the people capacity to adapt therefore adding to post-horrible issues. The greater part of the veterans that were associated with the Iraq war encountered probably the most interminable Post-Traumatic Stress Disorders. The seriousness of these scatters anyway relied generally upon how much the casualty was uncovered. Survivors of PTSD are accounted for to display three particular gatherings of manifestations (Wilson, Friedman and Lindy 336). Among these is excitement which is described by need oof focus, the casualty will in general keep away from the individuals around him, absence of rest, speedy in irritated and so forth. Re-encountering is another gathering of side effects which incorporates bad dreams, upsetting musings, continuing flashbacks and passionate Distress when the casualty recollects of the awful mishap. The other gathering of side effects is shirking in which the casualty will in general abstain from thinking about the occasion, the casualty gets dormant and grows low worry in exercises, s/he will in general keep good ways from the othe rs and his feelings become numb (Wilson, Friedman and Lindy 336). A portion of the war impacts that the veterans and their families experienced included loses of their friends and family. The majority of these officers when they came back from the war ended it all on account of the anxieties that continue frequenting them (Korb and Duggan 5). Another impact of the war is separate. The pace of separation has been accounted for to increment at an extremely high rate particularly by those coming back from the war. This is because of the mental issues which add to sedate maltreatment, drinking and aggressive behavior at home which thusly lead to separate (Korb and Duggan 5-6). It is accounted for that one in each five officers coming back from the war is encountering or gives a few side effects of PTSD. This number accordingly totalizes to roughly 345,000 who have so far been analyzed of PTSD (Korb and Duggan 4). It can in this way be reasoned that Post-Traumatic Stress Disorders (PTSD) are mental issues that one endures when presented to horrible mishaps, for example, war, mishaps and so on. The impacts of the Iraq war were extremely extraordinary that they influenced both the members and their families because of the PTSD. A portion of the reasons for PTSD included absence of enough groundwork for the war, presentation to unnerving sights, for example, spoiling bodies, introduction to weapon discharging, natural and atomic weapons. The working and day to day environments in Iraq were additionally not positive and somewhat added to the odds of experiencing PTSD. The side effects of PTSD are gathered into three classes; excitement, evasion and re-encountering. These side effects have been analyzed in more than 345,000 fighters that came back from the war. Purchase custom Post-Traumatic Stress Disorders exposition

Friday, August 21, 2020

The habeas laws Essay Example | Topics and Well Written Essays - 2500 words

The habeas laws - Essay Example . The striking ones among these incorporate the Vietnamese war, the war with the Iraqi government under the solid administration of the acclaimed President Sadam Hussein, the war against Osama canister Laden and his Afghanistan based fear based oppressors gathering, The Al Qaeda, normally known as the war on dread are probably the most perceived wars that the America government has battled since the finish of the virus wars. The war on dread against the fear gathering of Afghanistan under the initiative of Osama receptacle Laden started because of the bombarding assaults on the twins tower and world exchange community Washington DC which prompted the demise of several individuals, handfuls getting away with wounds of different degrees and thousands around the globe lamenting for the loss of their friends and family, companions and family members. More than 700 detainees have been caught according to these assaults, two or three them have been attempted and discharged without fines while some of them, around 169 are as yet serving prison terms in GITMO, a jail inside a U.S. maritime base at Guantanamo Bay, ashore rented from the legislature of Cuba. The shrubbery organization picked on this land for the confinement of these detainees so as to get away from the legitimate difficulties that would emerge from the preeminent courts of America scrutinizing the validness for the inconclusive detainment of the detainees of war by the hedge organization in spite of the prerequisites of the habeas corpus laws which offers rights to the prisoners to be heard before confinement. The habeas corpus laws expresses that, any people kept by the legislature is qualified for a legal hearing to decide whether there is any legitimate reason for their confinement, that is, the law shields any prisoner from detainment lacking adequate reason or pro of which is in accordance with article 1, segment 9 of the constitution of the US of America which expresses that â€Å"The Privilege of the Writ of Habeas Corpus will not be suspended, except if when in Cases of Rebellion or Invasion the open Safety may require it. (Jackson, 2006, 312) This paper will look at the privilege of habeas corpus with regards to the war on dread on the offer to offer assurance to the prisoners at GITMO and it inception advancement and presence in the American and British setting today. The general importance of the privilege of habeas corpus in the U.S. Constitution The habeas laws discovered their way into the American constitution through the suspension laws characterized in the constitution of the United States of America which incorporated the normal laws of England. Subsequently this law was upheld by the authorization of the article 1 area 9, provision 2 of the constitution requesting that â€Å"The benefit of the writ of habeas corpus will not be suspended, except if when in instances of defiance or intrusion the open wellbeing may require it. (Turner, 2002, 115) Carpenter takes note of that from the beginning of this institution, the constitution of the US concurs each individual an undisputable option to make a supplication to the bureaucratic courts for the request of habeas corpus in the event of any type of detainment filled as professional se cases whereby the legislature is typically called upon to reply under the steady gaze of the court the consistent purpose for the capture and confinement of a person by state specialists (Carpenter, 1902, 25). The habeas laws were then transmitted down to the individual state governments which too permit their separate residents to appeal to the state experts in their own state courts regarding their individual state constitutions when they happened to be condemned by the state specialists. The government habeas didn't matter to those under police guardianship even up to the hour of the war on fear based oppression. So as to guarantee that state courts execute the government

Tuesday, May 26, 2020

Examples of Topics to Write About

Examples of Topics to Write AboutOne of the best ways to gain a feel for a topic is to make some examples of topics to write about. This will give you a small sample of the kind of things that interest you and will give you something to work with.Using this technique is a great way to get a feel for a topic. It's especially helpful when you are trying to develop ideas on your own that are not too far out of your comfort zone.It also helps when you are learning how to write. You'll have a base of knowledge to go off of. You can use that as a guideline in developing your own ideas. Of course, it won't be as easy to do as it is when you're starting out but the important thing is to understand that writing is an art.When you are working on a topic, try to find one of the different books on it or search the Internet. The Internet is a great resource for finding examples of topics to write about. Most of the topics that you will find in books are not usually what you will find online.The I nternet is really good for spreading common knowledge and making new friends. These can both be useful resources for you. It's important to be persistent in your pursuit of your goal.Remember, this is an art and there are a lot of books out there on writing. It's important to find one that has been written by an author who is reputable and has years of experience. As you continue to make more examples of topics to write about, you'll begin to see more opportunities.Examples of topics to write about will give you a feeling for the topic as well as giving you some ideas of how to approach it. By doing this it will make it easier for you to begin researching and making examples of topics to write about.

Saturday, May 16, 2020

How Proust Can Change Your Life - 941 Words

It is a beautiful seventy- five degrees, with the sun shining and calm breeze in the air. You are in your room with the window cracked and music softly playing in the background. You sit at your desk to start reading your history homework. Next thing you know you wake up and two hours have passed by. While your body might have just been tired, it is likely that you became bored with what you were reading. In Alain de Botton’s book, How Proust Can Change Your Life, de Botton writes about factors that effect a reader’s attention. It is important to be aware of these factors in your own writing so your paper isn’t boring to the reader. THESIS Everyone has experienced insomnia but most likely never wrote seventy pages about the experience. Proust wrote a novel about being unable to fall asleep and was given negative feedback. One reader said â€Å"I don’t understand a thing, but absolutely nothing. Dear Marcel Proust, stop being a poseur and come down to ea rth. Just tell me in two lines what you really want to say† (Botton 34). The author did not engage his audience in his writing. When the writing does not appeal to the audience, the reader is unable to relate to the author and becomes disinterested. In Joseph Williams book, Style: Lessons in Clarity and Grace, addresses how emphasis must be placed in writing. Emphasis can occur at the beginning or the end of a piece of writing. Williams states, â€Å"When readers build up momentum in the first nine or ten words of a sentence, theyShow MoreRelatedEssay about Loves Knowledge by Martha Nussbaum1325 Words   |  6 Pagesimplicitly depicted as an impairer. I did manage to find a great example of love as an enhancer in Nussbaum’s Loves Knowledge. Love impairs our judgments and makes us do ridiculous things that we only do whilst in love. The impaired nature of our minds can be both beautifully displayed in the most innocent of ways or completely strange and misguided. But when enhanced, beautiful cognition of one’s self occurs. A jolt of something so real and all knowing happens, cataleptic impression. In Nussbaum’sRead MoreLaw of Constant Composition Lab: Magnesium and Oxygen1411 Words   |  6 PagesPurpose: To determine the percent magnesium by mass in magnesium oxide and to observe if the percentage composition is constant by comparing class results. Hypothesis/Prediction: The percent composition by mass of magnesium in magnesium oxide will not change significantly with each group that conducted the experiment. The composition of each substance should stay the same and any differences must be due to some error. Materials:Magnesium stripCrucibleCrucible coverClay triangleIron ringRetort standTongsBalanceBunsenRead MorePsy Chemical Senses1298 Words   |  6 PagesThe human body is very unique and amazing. Everything that we do in our daily life has a process that our body goes through just to make these things happen. It is so many elements phases that our brain goes through for our body to smell or taste something. So let’s explore this journey of smell and taste. Impacts of smell and taste When we taste something it is a process. Molecules enter the body in a solid or liquid form. They stimulate taste receptors on the tongue. There are five basic tasteRead MoreResponse to George Berkeleys Three Dialogues between Hylas and Philonous1009 Words   |  5 Pageswords, his argument is won. At his worst, Hylas attempts to use the word matter to mean what it truly does not mean simply by endowing it with new meaning. Even if language allows this, philosophical argument does not. Philonous objects: How many shapes is your matter to take?...you mean nothing at all... you employ words to no manner of purpose, without any design or signification whatsoever (Berkeley 54, 57). Philonous, the philosopher, wanting to describe his thought-world precisely, attemptsRead MoreThe Giver by Lois Lowry914 Words   |  4 PagesMarcel Proust once said, â€Å"The real voyage of discovery consists not in seeking new landscapes, but in having new eyes.† The protagonist, Jonas, in Lois Lo wry’s book The Giver, goes through a similar experience when he discovers his â€Å"Capacity to See Beyond.† Jonas begins to see his community differently, with a consciousness that most citizens in his community lack. When Jonas turns twelve, he is selected to be the next Receiver (who remembers for the community) because of his intelligence, integrityRead MoreA Persons Past and Memories Determine Who and What They Are895 Words   |  4 Pagesquotation explains us that we are successful in our present only because of our efforts and hard work in the past. Past is a key to present. I believe that system of change defines what we are and it is because one moment is not the same as the next that we are capable to feel and experience. Every experience teaches us lessons for better life. Our past is packed with lessons for present and future. We learned from our good and also from our bad experiences. Some people think that we dont need pastRead MoreWorkplace Motivational Theory Essay998 Words   |  4 PagesMotivational Theory James Roberts PSY/320 January 21, 2010 Dr. Sarah Christensen Workplace Motivational Theory Assembling theories about how motivational processes work transpire through research on motivation and emotion and elude personal insights (Reeve, 2009). In assessing the scientific merit of motivational theories, hypothesis can spawn and put to objective empirical testing (Reeve, 2009). Motivational concepts one chooses should be meticulously chosen, and continuously assessedRead More Samuel Becketts Waiting for Godot as an Existentialist Play4416 Words   |  18 Pagescontrolled by a pre-existing omnipotent being, such as God. Estragon and Vladimir have made the choice of waiting, without instruction or guidance, as Vladimir says, He didnt say for sure hed come (p.14), but decides to wait till we know exactly how we stand (p.18). Albert Camus, an existentialist writer, believed that boredom or waiting, which is essentially the breakdown of routine or habit, caused people to think seriously about their identity, as Estragon and Vladimir do. In The PlagueRead MoreThe Feminist Theory Of Women s Representation On The Company Board Of The Australian Agriculture Company Essay1706 Words   |  7 Pagesexamines elements of the feminist theory that reveal an insight to Women’s representation on the company board of the Australian Agriculture Company (AACo). Through the notion of gender, feminists analyse relations of power concerning males and females, how that power is exerted and the that interaction has habitually, historically and socially implemented over time. There are four major lenses of feminism; liberal, Marxist, radical and socialism. The findings in this paper focus on the strengths and limitationsRead MorePros and Cons of Using Electronic Gadgets in Studying1694 Words   |  7 PagesSome scholar s actually have stated that our brains are evolving and changing due to exposure–repeated exposure–to various activities on the computer. These changes have impacts on the traditional teaching-learning situations in classrooms and schools–particularly if one want to keep or focus the attention of students. In short, these so-called traditional teaching-learning style and practices might not be effective for the roaring digital minds. Does the use of digital technology really improve

Wednesday, May 6, 2020

Essay on Speech Pathology - 971 Words

SPEECH PATHOLOGY Many people would like to make a difference, not only in their own life, but in others’ lives as well. Deepak Chopra once said, â€Å"Everyone has a purpose in life†¦a unique gift or special talent to give to others. And when we blend this unique talent with service to others, we experience the ecstasy and exultation of our own spirit, which is the ultimate goal of all goals.† All of us, at one point in our lives, have to make the difficult decision of the goals we want to work towards. We all have certain goals, standards, and expectations of ourselves. Not everyone will figure out what they want to be right away, and some will know from the very beginning. My plan for my life is helping others through Speech Language†¦show more content†¦This job is not physically demanding, but it requires concentration and attention to details. A normal week for an SLP is approximately forty hours, with the possibility of traveling. There are ma ny requirements that involve education and training, as well as personal requirements and aptitude. To be a Speech Language Pathologist, one must have a sincere interest in helping people, sensitivity, resourcefulness, and imagination. One must also be able to communicate orally and in writing. Michigan Works, an agency that assists with employment, posts jobs that display education and background requirements for obtaining a job as a Speech Language Pathologist. Some requirements include a master’s degree from a speech and hearing program certified by the ASHA, American Speech and Hearing Association, post-certification experience in an institutional setting. Home health experience is also desirable. One must graduate from high school and pass courses in biology, physics, social sciences, English, mathematics, public speaking, language, and psychology. Undergraduate courses should include a strong Arts/Science focus, linguistics, phonetics, anatomy, psychology, human development, biology, physiology, math, physical science, semantics, and social/behavioral science. To be an applicant for an SLP position, a graduate degree is required and also three hundred to three hundred seventy-five hours of clinical experience. Applicants have to passShow MoreRelatedAn Interview with a Speech Pathology716 Words   |  3 PagesDuring my interview with Speech Pathologist, Deborah Kirsch, I learned countless details about the Speech Pathology career field. When we first began talking, I learned that Mrs. Kirsch works out of a company called â€Å"Professional Therapy Services†, where she is contracted out to work for â€Å"Eunice Smith Nursing Home† which is located in Alton, Illinois. She has been working at this facility for about a year. She is a newly found graduate from Southern Illinois University Edwardsville, and she graduatedRead MoreA Career in Speech and Language Pathology1414 Words   |  6 PagesA Career in Speech and Language Pathology Walking into school, a little boy is scared to talk to his classmates because he stutters . He is not getting good grades because he has trouble understanding information and communicating. His parents want to help him ,but do not know how. That is when speech and language pathologists come to the rescue. Speech and language pathologists help kids, teens, and adults overcome their oral and mental difficulties. They specialize in the field of helping theRead MoreMy Path Into Speech Pathology972 Words   |  4 Pages During high school volunteering at Columbus Regional Healthcare System led me to my path into Speech-Language Pathology. Since high school I was accepted into the Speech Pathology program and I apply to the graduate program this semester. Vidant Medical Center would be a wonder service-learning site to gain valuable career experiences. I would have the opportunity to incorporate my knowledge from previous classes with hands on experience with patients and st aff members. Vidant MedicalRead MoreIncreasing Cultural Competence in the Field of Speech-Language Pathology1018 Words   |  4 Pagesâ€Å"Raise your hand on the side that you hear the sound. Now open your mouth and stick out your tongue for me. Close it and then make an ooo sound, like a ghost.† This is what a brief clip of a speech and language evaluation might sound like if someone were to be observing. But imagine that the test that was just observed was over and now the clinician must speak to the parents; however, they can only speak to one: the father, due to the strict Muslim culture that the family comes from. What shouldRead MoreBenefits Of Speech-Language Pathology Services1003 Words   |  5 Pagesfrequently debated by the legislature concerns funding of various social/public programs which include speech-language pathology services. As a child who suffered from an auditory processing disorder, and a future licensed Speech-Language Pathologist (SLP), I know al l too well how important SLP services are for children. Currently, funding for social/public programs to include Speech-Language Pathology services in the United States is not adequate for children with learning disabilities and the legislatureRead MoreEmotional Intelligence And Speech Pathology Students1016 Words   |  5 PagesINTRODUCTION Therapy students, including those studying occupational therapy, physiotherapy and speech pathology, often experience difficulties during clinical placements in the final stages of their university program. These difficulties are occasionally so pronounced that students fail their clinical placements REF. The difficulties during clinical placements are related to a range of underlying reasons including underdeveloped communication, interpersonal, intrapersonal and social skills interactingRead MoreWhy I Became a Speech Pathologist Essay741 Words   |  3 Pagesgrandmother had a stroke which ultimately affected her speech and was in dire need of a Speech Pathologist. This is what initially sparked my interest in this field.  I was determined on working with the geriatric population because of the experience and attachment I endured with my grandmother. However, the irrefutable fact that this is my passion became evident when I started working as an Assistant Teacher at Clarke Schoo ls for Hearing and Speech. At Clarke I currently teach in a self contained classroomRead MoreWhat Career Choices Will You Have Made?806 Words   |  4 Pagesfor a Masters in Speech-Language Pathology. For 10 years, I would have worked as a Special Education Teacher. At the end of my tenth year teaching, I would take classes over the summer to work on a Masters in Speech-Language Pathology. I would start back teaching once I completed the program, own a private practice as a speech therapist, and own a non-profit store that collects clothes and sends them directly to families in need. During the Summer months I would work as a Speech-Language PathologistRead MoreEnglish Language Learners: Speech-Language Pathologists681 Words   |  3 PagesSpeech-language pathologists play a significant role in evaluation and intervention with English Language Learners. More and more SLPs are playing a teacher role in the academic environment. The role and responsibility of a speech-language pathologist is essential when identifying the most ethical and appropriate services to meet the individual needs of the student. However, evaluating ELL students can be challenging from a clinical standpoint and typically is complicated by many factors includingRead MoreThe Theory Of Language For Children With Language Impairments, And The Zone Of Proximal Development Essay1584 Words   |  7 PagesSpeech language pathology is a constantly evolving field. In truth, assessment strategies and therapies are constantly being improved because of the influences of Swiss biologist Jean Piaget (1896-1980) and Russian psychologist Lev Vygotsky (1896-1934), who developed theories of cognitive development among children. While these theories are similar in some ways, they also have key differences, such as the fact that Piaget thought children developed through stages, whereas Vygotsky stressed a more

Tuesday, May 5, 2020

Accounting for Managers Advanced Computer Technology

Question: Describe about the Accounting for Managers for Advanced Computer Technology. Answer: Problem 1: i) Depicting the faster process that might be used to increase competitive edge of the company: The faster process could only be applied by using advanced computer technology in the engineering and administrative department of the company, In addition, the use of computers has mainly reduced the overall time gap, which mainly occurred by transferring the data from one operations to other. Furthermore, the implementation of advance machines might also help in reducing thy overall time of completion of finished goods and decrease the process time. Davenport (2013) stated that advancement in technology has mainly help companies automated their operations, which in turn has reduced the completion time and cost of production. The reduced process time in engineering might mainly help the company to produce more goods, which in turn could help in increasing the supply and reduce cost of production. Moreover, the implementation of new technology could not only reduce process time but also help companies to reduce the labour costs incurred in their production process. In addition, the use of technological boost in administrative areas could effectively help the company to make adequate investment decisions and calculate the overall costs, which might be incurred in near future (Kieling, Brei and Vieira 2016). ii) Depicting the reasons for implementing improved quality for companies having reduced process time: The company that is able to work faster and reduce its process time mainly loses its focus on quality, which in turn might affect the overall customer satisfaction. In addition, a faster processing company could only focus on time and ignore the quality that is been produced. Schonsleben (2016) stated that customers are mainly focused on quality and ignores products that have low quality, which in turn affects profitability of faster processing companies. In addition, the implementation of increased quality might help faster processing companies to improve their overall product quality, which in turn might help in raise their customer base. In addition, the improved quality with faster process could help the company to raise its production quality and produce goods in faster rate. In this context, Yao et al. (2012) stated that companies that have reduced process time mainly ignore the quality checks, which mainly help in detecting faulty products. On the other hand, Wiles and Watts (2014) criticises that increased inspection conducted in the manufacturing process mainly reduce the ability of the company to reduce their completion time. In addition, companies could effectively reduce its process time by implementing advanced technology, which is not possible in case of improving their quality. iii) Depicting the problems that might be raised from increased speed process: The potential problems that might arise from increased speed of process are depicted as follows. Low quality and no improvement in products: The main problem that the high-speed process has is that it is not able to maintain the quality of the finished products. In addition, the company is not able to implement any kind of changes to their products as demand by the customers. Furthermore, any changes in the product design might mainly reduce the overall speed of the process and hamper completion time of the finished goods (Al-Mansour et al. 2014). Focused on process and not in customers: In addition, the other problems that might be faced by speedy process are that it is more productivity centric and not customer centric. The demands of the co customers are neglected and only reduction in production time is focused. Beesley (2013) cited that companies that are mainly production centric are not able to increase their demand, which in turn reduces their overall profitability. The depiction of these problems might mainly help in understanding the need of quality in the manufacturing process. Moreover, the company could find an equilibrium with production and quality to reduce the cost and maintain the level of demand in the market. Problem 2: i) Commenting on the overall observations of the case: The observation that been conducted by Steve Smith is mainly based on the overall income and the inventory balance of the two branches. However, the observation is mainly one sided as Steve Smith only looks in to the overall net profits that is been generated by both the branch. Moreover, he did not see the overall reduction in inventory that is been achieved by Adelaide, which might be conducted due to the implementation of absorption costing. In addition, the observation does not consider the overall impact of absorption costing, which might be affect operations of the both the branch (Chen, Kok and Tong 2013). ii) Depicting the conflicts that might be created if the company decides the business based on net profits: The company mainly provides bonuses based on net profits generated by the both the branches. However, this method might raise some conflicts as it mainly ignores the additional inventory accumulated and reduced by both the branches. In addition, the company also neglects the fact that implementation of absorption costing could have positively or negatively affected the overall profitability of the company. Moreover, XYZ policy could mainly reduce the efficiency of the managers in reducing the inventory and focus on sales. The negligence of efficiency and management control might mainly reduce the overall employee retention of both the branches. Rex and Outterson (2016) mentioned that bonuses are mainly conducted on basis of profits, employee loyalty and efficiency of the managers in conducting their operations. Moreover, increased conflicts among managers might reduce the overall productivity of the company. Problem 3: i) Depicting the variance significance regarding production cost for the period: The company has both material and labour variance present in its operations, which mainly affects its overall cost. In addition, the material variance is mainly conducted to identify the overall difference between actual cost of direct materials and standard cost of market. Moreover, the company to identify the low or high number of quantities consumed in its activities mainly uses the material variance. In addition, with the help of material variance companies are able to detect the actual cost inputted through their manufacturing process. Moreover, the labour variance is mainly conducted to identify the difference in actual and standard rate used by the company to portray their actual labour cost. Furthermore, the favourable material variance mainly indicates that budgeted material is equal to the actual material used by the company (Hee et al. 2014). In addition, the material variance is favourable, which depicted that the material used by the company is same and does not have to incur any additional material cost. Moreover, the labour variance is negative, which only indicates that the company is not able to depict the actual wage rate, which in turn has mainly increased the overall cost of production. ii) Stating the further information needed by the management for analysing the production cost for the period: In addition, the company could effectively find relative information like adequate material usage and cost of labour from the variance analysis. Furthermore, with the help of variance analysis the company could effectively detect the favourable and unfavourable variance that might improve their overall future budget. Moreover, the company with the help of the production cost analysis are able to detect the adequate amount of material and labour hours that might be used to support their production needs. In addition, the variance analysis could effectively help in depicting the changes in standard rates, which could help in depicting the adequate costs in their accounting books (Memon et al. 2013). Moreover, the analysis of variance and production cost could effectively help the company prepare an effectively budget, which might help in supporting the future activities. Problem 4: i) Calculating the cost per unit for variable cost: Variable expenses Budget A Budget B Direct materials 260,000 360,000 Direct labour 40,000 60,000 Variable overhead 60,000 75,000 Variable selling and administrative expense 60,000 60,000 Total variable expenses 420,000 555,000 Total units sales 20,000 30,000 Variable cost per unit 21 18.5 ii) Depicting the reason for budget A has high cost and low sales forecasts: The lower and middle level management mainly conducts budget A, which is why it mainly focus on the costs incurred by the company. In addition, as budget A is conducted by low level managed it is not able to effectively depict the change in demand for the companys products. Furthermore, as the low level management are not provided with relative information regarding the increase in demand, which in turn resulted in high cost and low sales forecast in the budget (Einsele 2013). In addition, Budget A is mainly cost centric and depicts the adequate cost, which might be needed by the company to continue its operations. iii) Depicting the reasons for budget B has low costs and high sales forecasts: The senior management has mainly conducted the overall Budget B, which is more focused on depicting the increase in demand for the products of the company. This budgeting system mainly focuses on depicting the rise in future demand of products and does not effectively addresses the change in variable and fixed costs of the company. Moreover, the senior management are mainly keen on detecting the change in demand, which can be effectively seen in Budget B. In addition, the top down budgeting approach mainly help companies to build the required allocation for each department. Moreover, this approach also helps in reducing the wastage of resource allocation that might be conducted in the budgeting process. In addition, the top-level management with adequate research and survey are able to depict the adequate budget requirements and income that could be generated in near future (Le et al. 2014). Moreover, the top down approach mainly reduces the dysfunctional behaviour, which might be conducted by the company. iv) Depicting the ways in which participants could come to a consensus to the budget and depicting the advantage of this approach: Both the group could effectively participate to improve the overall budget of the company. In addition, the expenses part of the budget could be derived from budget A and sales part of the budget could be derived from Budget B. This mixed budget approach might mainly help in reducing the overall variance analysis of the company. The budget could be effectively divided between low level and high level, which in turn might help in supporting operations of the company. With the help of this approach the company could effectively reduce, the excess wastage for essential resources that might be conducted due to unavailability of limited information. In addition, the approach also helps in depicting the adequate money each department could need to continue their operations (Quere et al. 2013). Moreover, the approach could also help in develop a bond between low, medium and higher management of the company. Reference: Al-Mansour, F., Sucic, B., Pusnik, M. and Vuk, T., 2014, January. Novel concept of context sensitive energy and environmental management system for support sustainable development of industrial companies. Ineceee Industrial Summer Study RETOOL FOR A COMPETITIVE AND SUSTAINABLE INDUSTRY. Beesley, A., 2013. Time compression in the supply chain.Logistics Information Management. Chen, L., Kk, A.G. and Tong, J.D., 2013. The effect of payment schemes on inventory decisions: The role of mental accounting.Management Science,59(2), pp.436-451. Davenport, T.H., 2013.Process innovation: reengineering work through information technology. Harvard Business Press. Einsele, G., 2013.Sedimentary basins: evolution, facies, and sediment budget. Springer Science Business Media. Hee, L., Rasmussen, C.K., Schltter, J.M., Sandager, P. and Uldbjerg, N., 2014. Quantitative sonoelastography of the uterine cervix prior to induction of labor as a predictor of cervical dilation time. Acta obstetricia et gynecologica Scandinavica, 93(7), pp.684-690. Kieling, A.P., Brei, V.A. and Vieira, V.A., 2016. After some time using a product or service, the consumer tends to feel less pleasure with consumption. This reduction of pleasure is known as hedonic adaptation. One of the emotions that interfere in this process is surprise. Based on two experiments, we suggest that negative surprise differently to positive influences with the level of pleasure foreseen and experienced by the consumer. Study 1 analyzes the influence of negative (vs. positive) surprise on the consumer s post-purchase hedonic ....Brazilian Business Review,13(3), pp.111-132. Le Qur, C., Moriarty, R., Andrew, R.M., Peters, G.P., Ciais, P., Friedlingstein, P., Jones, S.D., Sitch, S., Tans, P., Arneth, A. and Boden, T.A., 2015. Global carbon budget 2014. Memon, A.H., Rahman, I.A., Aziz, A.A.A. and Abdullah, N.H., 2013. Using structural equation modelling to assess effects of construction resource related factors on cost overrun.World Applied Sciences Journal,21(5), pp.6-15. Qur, C.L., Andres, R.J., Boden, T., Conway, T., Houghton, R.A., House, J.I., Marland, G., Peters, G.P., Van der Werf, G.R., Ahlstrm, A. and Andrew, R.M., 2013. The global carbon budget 19592011.Earth System Science Data,5(1), pp.165-185. Rex, J.H. and Outterson, K., 2016. Antibiotic reimbursement in a model delinked from sales: a benchmark-based worldwide approach.The Lancet Infectious Diseases,16(4), pp.500-505. Schnsleben, P., 2016.Integral logistics management: Operations and supply chain management within and across companies. CRC Press. Wiles, C. and Watts, P., 2014. Continuous process technology: a tool for sustainable production.Green Chemistry,16(1), pp.55-62. Yao, Y., Huang, L., Sharma, A., Golubchik, L. and Neely, M., 2012, March. Data centers power reduction: A two time scale approach for delay tolerant workloads. InINFOCOM, 2012 Proceedings IEEE(pp. 1431-1439). IEEE.

Wednesday, April 15, 2020

Frustration and Its Consequences

My friend Deb really frustrates me with her illness issues. Deb and I graduated from high school together and have remained close friends throughout the years. About five years ago, doctors diagnosed her with fibromyalgia and rheumatoid arthritis. Since then, her behavior has changed to somebody different, which actually frustrates me.Advertising We will write a custom essay sample on Frustration and Its Consequences specifically for you for only $16.05 $11/page Learn More I however, sometimes feel that Deb’s behavior does not come from her illness; it has become a mental problem, which frustrates and worries me. My thesis in this essay is that Deb’s behavior is no longer a result of illness but mindset. Based on her condition, I will demonstrate how her mentality has changed her behavior. Deb is always reflecting on the illness. While in high school, Deb was a bubbly, outgoing and a fun person; since the diagnosis however, she has changed from that kind of a person to someone who complains constantly of some illness. Even at times when she is not suffering from any pain, she complains of how she suffered the previous night or how she is likely to suffer the coming night. Her plans and thoughts revolve around the illness and this ends up frustrating all our plans. If we have made plans to do something, inevitably and regrettably a day or two before, she will call and cancel due to illness. The illness of other people reminds Deb of her sickness even when she is not suffering from any pain. My little knowledge on fibromyalgia informs me that people with this condition experience pain periodically, not as frequent as Deb insinuates. What frustrates me further is that when other people note to have a cold, sore back or anything, she will change the subject to her condition and something worse. Why should the situation of other people worsen her ill condition? I attribute this to her mindset. Looking at her physically, ev en when she is not suffering, she seems disturbed. She is always concerned about pills and her doctor. Whenever we are moving out, she has to carry her pills. This has set her mind such that she carries the pills even when she is not going far from the house. She always needs a pain pill for this or need to go to the doctor for that, and honestly this behavior worries and frustrates me.Advertising Looking for essay on psychology? Let's see if we can help you! Get your first paper with 15% OFF Learn More While sometimes I can justify her need for the pills, her carrying the pills most of the times is habitual. I am afraid that she is becoming addicted to being sick and the pills. In fact, she is ever discussing her encounters with the doctor, which frustrates me. I love her and just want her to get back to the person I initially knew. I am ever in contemplation on how to help her. Sometimes I think of consulting a psychiatrist for her situation but since she is so engro ssed with the fibromyalgia doctor, I find it difficult to convince her. In fact, it might cause more damage to her condition. I am therefore frustrated and I do not know how to help her. Her addiction to being sick, pills, discussing about her doctor and her illness really disturbs me. We no longer share the moments we used to; no outing or fun any more. Her illness has considerably affected her and her behavior is no longer a result of the illness but the mindset. In life, things are formed twice; in the mind and in reality (physically). Therefore, it appears Deb has formed a sickness in her mind and that’s what manifests in the physical. This essay on Frustration and Its Consequences was written and submitted by user Ada O. to help you with your own studies. You are free to use it for research and reference purposes in order to write your own paper; however, you must cite it accordingly. You can donate your paper here.

Thursday, March 12, 2020

drama improvisation essays

drama improvisation essays processes for the Elizabethan period In this essay based on improvisation, and the process that we undertook in the play building process I will describe the processes and stages that we went through but first, the main period of time that inspired our drama play was Elizabethan, theater during the Elizabethan times was often based around the lives and deaths of monarchs (kings and queens). Our play relates to the conventions of theater at the time because it was based around monarchs. The central purpose of this play was to point out the amount of superstition and envy that was often in the royal family but never seen by the public, as well as to entertain and educate the viewing audience about the Elizabethan times and what the Elizabethan plays were about and the sort of characters that were involved in these sort of plays: witches, kings, queens, princesses, soldiers, lady in waiting, and princes. As well as any other characters that may be required. The characters of out play are representative of characters of the sixteenth century because the witch planted a seed of ambition in the princess and the king goes off to battle, and the queen receives a report that the king is missing in action and presumed dead. The princess thinks that she should be the one to assume the throne because she is older than her brother but, when her brother is crowned heir to the throne the infuriated princess goes to the witch for a prediction of the future. This is where the witch plants the seed of ambition; this is an example of representation of characters of the sixteenth century. The plot of our drama performance was a reminiscent of the sixteenth century because there are witches, but the main similarity between our play and a drama performance of the sixteenth century is that in the sixteenth century drama a monarch was usually killed, in our play a monarch was also killed, the monarch tha ...

Tuesday, February 25, 2020

COMMONWEALTH of Pennsylvania, v Paul David CREWS Research Paper

COMMONWEALTH of Pennsylvania, v Paul David CREWS - Research Paper Example The case study of commonwealth of Pennsylvania vs. Paul David Crew is among the most valuable perspective pertaining to the use of DNA evidence in solving crime. The sensitive treatment of victims in DNA cases is essential across the entire criminal justice system; first beginning with the arrival of the responders at the crime scene and then continuing until long after suspects are convicted. All types of victims especially sexual assault victims should be subjected to fair and sensitive treatment with respect and dignity, especially during the collection of biological evidence from a wider range of crime scenes, which is now beginning to regularly occur in the United States. Problems regarding the security and privacy of a victim’s information in DNA cases are a major concern. The Victims’ DNA profiles are characteristically entered into databases which cause many victims to worry about the privacy of this information, whether it can be accessed by the perpetrators th rough the local databases or the internet. There is also concern about whether this technology can be used against victims who may have committed other crimes, which can possibly result in a decrease in reporting (PLJ, 2012). In this research paper, I chose the case of Commonwealth of Pennsylvania versus Paul David Crews in which many unique talents pertaining DNA evidence were involved in prosecuting the culprit. I am going to study facets of this case which I deem necessary to mention for the purpose of this research. Here, there is a combination of professional unique talents, the respect, their dignity and strive to foster their commitment to excellence in their work that led to justice. Unity and diversity of people on the free exchange of ideas, on learning, living and working harmoniously is truly the pillar of a community’s strength in society as we shall observe in this paper. For the purpose of grasping the whole concept of the case, I will briefly touch on other fa cets of the case other than those pertaining DNA evaluation. It is the professional unbiased performance of each that slowly but surely led to justice (PLJ, 2012). Commonwealth Of Pennsylvania, V Paul David Crews In the morning of September 13, 1990, two hikers, Geoffrey Hood and Molly LaRue, were murdered .The woman tied, raped, and stabbed, resulting to her death. Her boyfriend, shot three times. The suspect Paul David Crews was arrested week later and subsequently charged with the murders. There were a number of witnesses who presented themselves to testify. The first witnesses testified seeing the suspect visit a library seeking a map of the terrain where the couple was murdered while other witnesses testified the suspect seeking directions of the trail that coincidentally was the same with those of the murdered couple. These witnesses openly shared their knowledge to the relevant authorities. Some even vividly testified of seeing the suspect wearing the hiking gear belonging to the male victim along with other objects. A ballistics expert also testified that the handgun possessed by the suspect upon his arrest was the murder weapon which. An FBI DNA expert, after caring out his unique duty came to a conclusion thus testifying that the suspects DNA patterns matched with those obtained from semen samples the female victims vagina. The jury which comprises of carefully selected individuals of varying personalities and background

Sunday, February 9, 2020

How newspapers will use social media and internet to expand readership Term Paper - 1

How newspapers will use social media and internet to expand readership in the future - Term Paper Example avvy world thus, the social media is strong enough to take over the traditional forms of transmission of news like newspapers, radio, television etc due to faster and better communication among people, rapidity of spread of news, an increase in readership, as well as a growing need to adapt and become environment friendly. Newspapers and radio channels are far behind than television today in terms of the spread of news for the sole reason that with the click of a channel or press of a button one can both see or hear the news on the go, as and when it takes place. Newspapers, even though they provide the audience with a chance to spend time reading and enhancing their knowledge, arrive a day later, by which time the person may already be well versed with the news. Newspapers however have a tangible form that many people are attached to and not willing to give up. Yet, it must be understood that newspapers can make use of the social media in order to expand their readership in the future as more and more people are logged onto the internet these days. Students, workers as well as professionals and home makers – almost everyone and anyone have an account on a social networking website. Thus in order to tap the potential, newspapers can exploit these platforms and display their news banner there, a ttracting readers onto their websites and thus help them in enriching themselves by displaying their news. (Rani Malla) Today, a number of newspapers have online editions, like Wall Street Journal and New York Times to name a few; these newspapers put up everything and more on their online versions, where people may subscribe and get hourly updates on the world’s events. Newspapers can also take over social networking websites to attract more readers by creating their pages and groups and involving forums for communication over the news among various people. Moreover, blogs and online journals are encouraged by newspaper reporters and writers in order to increase

Thursday, January 30, 2020

Anti-Cancer Drug Screening in Vitro Essay Example for Free

Anti-Cancer Drug Screening in Vitro Essay Introduction: The incidences of cancer remain high despite advances in our understanding of cancer. Cancer is a class of diseases characterized by out of control cell growth. Normal cells are constantly subject to signals that control whether the cell should divide, differentiate into another cell or die. Cancer cells develop a degree of independence from these signals, which results in uncontrolled growth and proliferation. If this proliferation is allowed to continue and spread, it can be fatal (1). Almost 90% of cancer-related deaths are due to metastasis – the complex process of tumor spread through the lymphatic system or bloodstream. The emergence of genomic technologies holds therapeutic potential for personalized cancer management. Personalized cancer management combines standard chemotherapy and radiation treatments with genomic profiling and in vitro cell proliferation studies. Individualized genomic profiling allows the researcher to identify specific genes that contribute to unregulated cellular mechanisms that normally control cellular growth. By determining the molecular profile of a specific cancer, suitable treatment can be considered that target those gene products (2). Cultured cancer cells have the capacity to dramatically exceed normal doubling times to almost indefinite levels, unlike normal cells. HeLa cells are a great example of this. One of the most widely used continuous cell lines in research is the HeLa cell line, which was derived in 1951 from Henrietta Lacks, a cervical caner patient in 1951. These cells continue to grow and proliferate in hundreds of laboratories across the world to this day. These cancer cells have been called ‘Immortal’ as they have bypassed the senescence regulators within the cell and acquired the capacity for unlimited division. Measurement of cell viability and proliferation forms the basis for numerous in vitro assays of a cell population’s response to external factors. The reduction of tetrazolium salts is now widely accepted as a reliable way to examine cell p roliferation. MTT viability assays is based on the ability of a mitochondrial dehydrogenase enzyme from viable cells to cleave the tetrazolium rings of the pale yellow MTT and form a dark blue formazan crystals, which is largely impermeable to cell membranes, thus resulting in its accumulation within healthy cells. The resulting  intracellular purple formazan can be solubilized and quantified by a spectrometer and is then subject to examination to evaluate cell viability. These measurements can be used to evaluate the effectiveness of certain treatments to cells. These anti-cancer drugs in vitro allows drugs to be tested against live cells which helps determine drug effectiveness and side effects. Cell proliferation, also known as cell growth, cell division, or cell replication is the basic process through which cells form new cell. Cell proliferation is the increase in cell number as a result of cell division and growth. The quantification of cellular growth, including proliferation and viability, has become an essential tool in any laboratory working on cell-based studies. These techniques enable the optimization of cell culture conditions, and the determination of growth factor and cytokine activity. Even more importantly, the efficiency of therapeutic agents in drug screening, the cytostatic potential of anticancer compounds in toxicology testing, and cell-mediated toxicity can be assessed when quantifying cell growth (3). This practical is designed to evaluate the sensitivity and response of putative anti-cancer drugs using a modified anti-proliferative drug assay. Using a modified MTT drug assay, the sensitivity and response of anti-cancer drugs can be determined. In this blind trial, three unlabeled drugs are tested to discover their properties. The trial of these drugs was carried as a blind trial to insure that the results obtained with unbiased. Results In this practical, we were given three drugs. One of the drugs had no known anti-cancer properties; one was a known chemotherapeutic agent and the third was a mystery drug with putative anti-cancer properties. The HeLa cells were also treated with a no-drug, medium-only control. The objective of the study was to identify the nature of the unlabeled drugs. The identities of these three drugs were unknown in order to make the experiment a blind trial. Doing the study as a blind trial allowed any bias data to be avoided in data interpretation (2). Calculations: From the raw data obtained column 0 acts as the control, this column contains the HeLa cells but no drug, and is used to see if the unknown drugs A,B and  C have an effect on the viability of HeLa cells. The last row on the 96 well plates contained no HeLa cells and acted as a reference to observe whether column 0 contained living cells. When the absorbance value for column 0 was similar to the no cell value, that data set would be ignored, as this would indicate no cells were present in column 0 which would have been invalid as column 0 contained medium only. This method was applied when choosing appropriate data sets for data interpretation. Discussion: In this study we were given three drugs. One of the drugs had no known anti-cancer properties, one had a known chemotherapeutic agent and the third was a mystery drug with putative anti-cancer properties. The objective of this blind trial study was to identify the nature of these unlabeled drugs.  By observing the overall averages from the results (Table 1 Figure 1) we can conclude that drug A had the highest percentage cell viability out of the three drugs. The percentage value of A is similar to the percentage value of the control (0). The control consisted of a medium-only solution and not meant to effect the cell viability of HeLa cells at all, this implies that Drug A has no anti-cancer properties and has little effect on the HeLa cells viability. From this data we can conclude that Drug A was the drug with no known anti-cancer properties (negative control). By observing the percentage cell viability of drug B, we can conclude that drug B had the smallest cell viability value that was close to 0%. Small percentage viability indicates that there is a reduction in cell proliferation occurring in the HeLa cell line, however 0% cell viability would indicate that there are no viable cells in the well, meaning there was a complete reduction in cell proliferation. Lack of cell proliferation means an absence of mitochondrial succinic dehydrogenase activity to metabolize MTT into its results purple formazan, producing a lower absorbance value (4). From this we can conclude that drug B has anti-cancer properties as it had a large negative effect on HeLa cell viability. By observing drug C, we can determine that drug C also has a relatively low percentage cell viability value. This would indicate that drug C, like drug B, has a negative effect on cell viability, meaning it causes a reduction in cell proliferation in HeLa cells. From this we can conclude that Drug C also had anti-cancer properties as it had a negative effect on HeLa cell viability. At this point, two drugs have yet to be identified, Drug B and Drug C. Both Drug B and Drug C have anti-cancer properties, shown by their low cell viabilities values. A positive control will be a drug that will give a large cell viability percentage. From this, we would conclude that Drug B was the positive control with a chemotherapeutic agent leaving Drug C to be the mystery drug. However we cannot accept this without actually knowing what the mystery drugs anti-cancer properties are. The mystery drug could have stronger anti-cancer properties than the positive control. In this scenario, Drug B would be the mystery drug as it observed the lowest cell viability, making it the most effective against cancer cells. For this reason, we cannot accurately identify drugs B and C without more information about the mystery drug. However if we accept that the mystery drug has a smaller  effect on cancer cells than the positive control, we would then conclude that Drug B is the positive control and Drug C is the mystery drug. If we observe the overall data used to calculate the average cell viability percentages for each drug, we can see there are values higher than 100% and values lower than 0% (negative values). Values higher than 100% would indicate that there are more viable cells present in drug A compared to our control. Since we know drug A has no effect on the cancer cells, we would expect the cell viability of drug A to be similar to the control. These anomalies could be due to cell proliferation in the drug A column, meaning the HeLa cells grew and divided to create new cells, meaning the number of cells in column A increased, resulting in a higher absorbance value, due to the increase in MTT reduction. A higher absorbance value in the no cell row compared to the drug B column results in a negative value. Absorbance values that are lower than the control cells indicate a reduction in the rate of cell proliferation. Conversely a higher absorbance rate indicates an increase in cell proliferation. Values lower than 0% would indicate that there are fewer cells present in the drug B wells compared to the no cell wells. This could be due to human error where cells where accidently transferred due to poor lab technique, or been caused by a high absorbency of the buffer used in the no cell row. In this study, the reduction of the MMT is used to estimate cell viability and proliferation. However recent studies have shown that superoxide can also reduce tetrazolium salts, such as MTT. Therefore studies investigating the cytological effect of HeLa cells may encounter misleading results when using MTT to measure viability proliferation. This is because MTT assays may yield inaccurate results due to the increase in superoxide formation in cultured HeLa cells (7). This kind of limitation may have played apart in this study and could have caused our abnormal values discussed in the paragraph above. To overcome this limitation, we could use different techniques to measure cell viability. One way of assessing cytotoxicity is by cell integrity. Compounds that have cytotoxic effects, such as the drugs we are investigating, often compromise cell membrane integrity. An example of this method is a Tryphan Blue exclusion test (10). This exclusion test can be used to determine the number of viable cells present in a cell suspension. It is based on the principle that viable cells have intact cell membranes that are impermeable to dyes,  such a trypan blue, whereas dead cells do not. In this test, a cell suspension is mixed with the tryphan blue dye and then visually examined to determine whether cells take up or exclude the dye (11). A viable cell will have a clear cytoplasm whereas a dead cell will have a blue cytoplasm. Tryphan blue is not affected by superoxide formation so will yield more accurate results than the MTT assay. The problems that arise from dye exclusion tests is that they are operator depend and are subject to human error. Another way of assessing cell viability via membrane integrity is by using fluorescent DNA binding dyes such as SYBR Green I (10). SYBR Green I is a fluorescent dye used as a nucleic acid dye. SYBR Green I binds to DNA and the resulting DNA-dye-complex absorbs blue light and emits green light (9). This is based on the principle that an increase in cell proliferation will cause an increase of DNA in the cell suspension. More SYBR Green 1 will bind to the DNA and more green light will be observed under blue light.

Wednesday, January 22, 2020

Hawthorne: An Inescapable Burden :: essays research papers fc

An Inescapable Burden   Ã‚  Ã‚  Ã‚  Ã‚   A young boy’s parents did not get the opportunity to attend college and they divorced when he was only seven. His father was addicted to crack cocaine and his mother began to sell herself as a source of income. He was tossed back and forth between the two houses and used as a way for the two parents to get back at each other. As a result, this boy grew up to be a criminal and was thrown in jail for selling drugs for his father. This life of crime and debauchery was all that he knew. He constantly paid for the mistakes of his parents and his parents’ parents. This is a common event that has taken place in human society throughout time. Nathaniel Hawthorne recognized the fact that people have the burden of constantly dealing with the shortcomings and lack of opportunity that come with many mistakes that parents make. This theme and realization of Hawthorne’s is a prevalent theme in many of his stories. This theme and idea that one must pay for the mistakes of his o r her forefathers is displayed not only in Hawthorne’s own history but in his stories â€Å"Dr. Rappacini’s Daughter,† â€Å"The Birthmark,† and â€Å"Young Goodman Brown† as well.   Ã‚  Ã‚  Ã‚  Ã‚  Hawthorne had a family history which he was personally ashamed of. He was born in Salem Massachusetts in 1804 with the emotional burden of having a great-great grandfather that was the judge that presided over the Salem witch trials (Gollin 1). This man wrongfully convicted many women that were put to death as a result of his conviction. The blood of these women was on his hands and it was probably the thought in Hawthorne‘s mind that his ancestor did the devil’s work . This family history is most prominently displayed in his story â€Å"Young Goodman Brown† as Goodman faces similar internal conflict during his journey (Gray 90). Hawthorne thought that his sea captain father paid for these mistakes as he was killed on a voyage when Hawthorne was four years old (â€Å"Nathaniel Hawthorne† 259). Hawthorne could have conceived this idea directly from God’s own word. The Bible claims that God will inflict â€Å"punishment for their f ather’s wickedness on the children of those who hate [him] down to the third and fourth generation† (Exodus 20.5). Hawthorne’s own personal family history imbedded this theme in his own theologies.   Ã‚  Ã‚  Ã‚  Ã‚  This theme is displayed in Hawthorne’s short story â€Å"Dr.

Monday, January 13, 2020

Imperialism and Manhood Essay

Study question 1. 2. 3. To Roosevelt, the idea of race suicide was closely interlinked to manhood. Not only would the American men face competition from immigrant workers and be unable to provide for more children: thus leading to an excess of inferior immigrants but the American man would also be related to the impotent American man, unable to create more children. This would lead to the race’s elimination Race and Immigration 1. It allowed individuals to distinguish and separate themselves from immigrants thus creating a barrier that showed them as undesirable. 2. Certain policies and laws were created to separate the Chinese from other groups: Chinese Exclusion Act. 3. This act set a precedent on the treatment of other foreigners that would enter America. Urban Politics and Culture 1. It is preferable to have a community that has a degree of refinement than to live in one that is full of poverty. 2. The wealth should be divided amongst the immediate family to a degree that does not surpass them into leading unfulfilling and lazy lives. The rest should be distributed for the benefit of society. 1. Having undergone poverty himself, Riles shows stereotypes but presents them in an entertaining way to the audience. Also he mentions the roles these different cultures play in merging with the American way of life. 2. Riis and Carnegie are similar in their opinion that the poor exist and cannot be ignored but it is only the rich who can provide them with relief. Cultural Encounters in the Far West 1. The Bison went into extinction because of the cold and droughts bought in by the changing environment and human influence which resulted in colonial expansion that bought in new diseases and animals. 2. It was not the nomads alone who hunted the bison. They sold the animals to the Euro-American invaders. 1. Blacks could not vote unless their grandfathers had not been voters before the Civil War, literacy tests had to be passed, fees was charged for voting and democrats (always white individuals) were the only ones allowed to vote. 2. The South contained individuals who had the deepest hatred for the blacks which led the lynching in this area to be the worst. 3. Separate schools, hospitals, accommodations and even entrances were given to the two groups. Often enough the blacks were provided no facilities by certain states. 4. They decided to test out the marginzalation itself by acts like the one committed by Homer A Plessy Jim Crow Museum of Racist Memorabilia Website 1. Minstrels would perform music with black faced performers in the quest to ridicule black people. Also caricatures were made which were printed in novels and plays. 2. Churches taught that blacks were inferior. Politicians gave speeches supporting segregation and writers also wrote against the black man.

Sunday, January 5, 2020

Analysis of Peter Skrynecki´s Migrant Hostel and 10 Mary...

Through an individual’s intrinsic desire to develop meaningful connections with society, place or heritage, they forge their own sense of self-identity by overcoming the barriers in place. In Peter Skrzynecki’s poetry, particularly â€Å"Migrant Hostel† and â€Å"10 Mary Street† we witness an individual’s experience of segregation to eventual connection in the world they live. Skrzynecki’s insightful poem â€Å"Migrant Hostel† explores the notion of impermanence and uncertainty in an individual’s experience where stability is essential to develop an identity and sense of belonging. The poem illustrates the disorientating nature of a migrant hostel where the people within yearn for sanctuary in the Australian community. This idea is instantly reflected through the negative connotations in â€Å"no one kept count† representing a sense of anonymity in the atmosphere through a lack of individual significance. The enjambment and juxtaposition of the â€Å"comings† and â€Å"goings† highlights the transient and uncertain nature of the hostel environment where they were â€Å"left wondering who would be coming next†. The intrinsic desire of human nature to develop meaningful bonds with people that share similar adversities is displayed through simile and symbol of a â€Å"homing pigeon circling to get its bearings †. Furthermore, the alliteration in â€Å"memories of hunger and hate† convey their previous experiences hindering their search for harmony and permission into the broader community. This notion is further